Are we appropriately testing for vitamin B12 and folate deficiency?
نویسندگان
چکیده
منابع مشابه
Causes of vitamin B12 and folate deficiency.
This review describes current knowledge of the main causes of vitamin B12 and folate deficiency. The most common explanations for poor vitamin B12 status are a low dietary intake of the vitamin (i.e., a low intake of animal-source foods) and malabsorption. Although it has long been known that strict vegetarians (vegans) are at risk for vitamin B12 deficiency, evidence now indicates that low int...
متن کاملFolate and vitamin B12.
The folates are made up of a pterdine ring attached to a p-aminobenzoate and a polyglutamyl chain. The active form is tetrahydrofolate which can have C1 units enzymically attached. These C1 units (as a formly group) are passed on to enzymes in the purine pathway that insert the C-2 and C-8 into the purine ring. A methylene group (-CH2-) attached to tetrahydrofolate is used to convert the uracil...
متن کاملErythrocyte Vitamin B12 Activity in Health, Polycythemia, and in Deficiency of Vitamin B12 and Folate
T HERE HAS BEEN RELATIVELY LITTLE WORK on the estimation of erythrocyte vitamin B12 activity in man, and consequently there are few reports of its activity in disease states. Sobotka et al.1 reported low levels in four cases of pernicious anemia ( P. A. ) , using E. gracilis and 0. maihamensis. This was confirmed by Biggs et al.,2 who also reported the levels found in treated cases of polycythe...
متن کاملErythrocyte vitamin B12 activity in health, polycythemia, and in deficiency of vitamin B12 and folate.
T HERE HAS BEEN RELATIVELY LITTLE WORK on the estimation of erythrocyte vitamin B12 activity in man, and consequently there are few reports of its activity in disease states. Sobotka et al.1 reported low levels in four cases of pernicious anemia ( P. A. ) , using E. gracilis and 0. maihamensis. This was confirmed by Biggs et al.,2 who also reported the levels found in treated cases of polycythe...
متن کاملCytogenetic observations in vitamin B12 and folate deficiency.
Writ/i the technical assistance of Miss Lila Fliegelnian O CCASIONAL REPORTS have presemited cytogenetic data from cases of megaloblastic anemia.ii,uul Although no consistemit cytogenetic abnormalities have yet beeii found, a variety of changes have been described in some cases of pernicious anemia.m’ ’m” The significance of these findings is not clear. This report describes cytogenetic observa...
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ژورنال
عنوان ژورنال: Annals of Clinical Chemistry and Laboratory Medicine
سال: 2018
ISSN: 2392-4446,2382-5081
DOI: 10.3126/acclm.v3i1.15612